We have received an approval for an O-1 for a pharmaceuticals scientist employed by a small company.  The case was approved without an RFE where we clearly showed the advanced nature of the work and the qualifications of the beneficiary.  The outcome of O-1 visa petitions is always unpredictable, and, as a practical matter, more so where the employer is a very small company.  Despite its size, the company was engaged in highly specialized and advanced level work.  In addition to the beneficiary’s qualifications, the nature of the work